Shawn Yazdani MD, FACC, FSCAI

Dr. Yazdani became interested in treating structural heart disease in 2012 when science supported the use of transcatheter aortic valve replacement (TAVR) techniques, in lieu of open heart surgery, to treat aortic valve disease, specifically aortic stenosis.

He was involved in the initial trials observing transcatheter therapy in patients at high or prohibitive risk for surgical valve replacement. Since then, he has served as primary investigator in many other trials, including Partner 3, Early TAVR, and Galileo. He has been the lead physician in bringing non-surgical alternative access, such as Transcaval valve replacement, to Northern Virginia – for patients who do not have good femoral access for valve delivery.

Dr. Yazdani has performed more TAVR procedures in Northern Virginia than any other operator.

He remains involved in research and continues to pioneer nonsurgical catheter based treatments.

Though only a few physicians were performing this procedure nationwide, he has since broadened it popularly and become instrumental in bringing to the area different mitral valve treatment modalities, such as Lampoon (laceration of the anterior leaflet of the mitral valve prior to transcatheter replacement of the mitral valve), to the area.

He is the primary investigator for the Apollo trials, involving transcatheter replacement of the mitral valve, or transcatheter mitral valve replacement (TMVR), in patients at high or intermediate risk for surgical valve replacement. He is also known for his expertise in mitral valve repair therapies such as MitraClip.

Dr. Yazdani is also involved in therapies geared towards patients with atrial fibrillation (AFib) and at high risk for taking blood thinners such as Coumadin.

He regularly performs implantation of Left Atrial Appendage (LAA) Occluders such as the WATCHMAN™ device.

Despite having a busy interventional practice, he also holds regular office hours in multiple locations in Northern Virginia including Vienna, Manassas and Warrenton.


Dr. Yazdani completed both his undergraduate degree in Biology and his medical degree at New York University.

His postgraduate training included a residency in internal medicine, followed by a Cardiology residency at Columbia Presbyterian Hospital. He then finished his interventional training at Mount Sinai Hospital.

Professional Affiliations